Prostate Cancer Clinical Trial

Prostate Cancer Clinical Trial Results

1. U.S. Cancer Screening Trial Shows No Early Mortality Benefit from Annual Prostate Cancer Screening
(Posted: 03/18/2009) - Six annual screenings for prostate cancer led to more diagnoses of the disease, but no fewer prostate cancer deaths, according to a major new report from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, a 17-year project of the NCI. The PLCO was designed to provide answers about the effectiveness of prostate cancer screening.

2. Radiation Plus Hormone Therapy for Locally Advanced Prostate Cancer Improves Survival
(Posted: 02/03/2009) - Clinical trial results published online December 15, 2009, in The Lancet, affirms earlier studies showing that adding radiation therapy to hormone therapy (HT) is more effective than HT alone for locally advanced prostate cancer.

3. Review of Prostate Cancer Prevention Study Shows No Benefit for Use of Selenium and Vitamin E Supplements
(Posted: 10/27/2008, Updated: 12/09/2008) - Initial, independent review of study data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by the National Cancer Institute (NCI) and other institutes that comprise the National Institutes of Health shows that selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer. The data also showed two concerning trends: a small but not statistically significant increase in the number of prostate cancer cases among the over 35,000 men age 50 and older in the trial taking only vitamin E and a small, but not statistically significant increase in the number of cases of adult onset diabetes in men taking only selenium.

4. Studies Make Case for Finasteride to Prevent Prostate Cancer
(Posted: 06/24/2008) - Three new analyses of data from a large prostate cancer prevention trial bolster the case for finasteride as a preventive agent against prostate cancer, according to an article published online May 18, 2008, by the journal Cancer Prevention Research.

5. Comorbidities May Limit Benefits of Combination Prostate Therapy
(Posted: 01/30/2008) - Men with localized prostate cancer who are also ill with other disorders may suffer more from the negative side effects of anticancer treatments such as androgen suppression therapy, according to the Jan. 23, 2008, Journal of the American Medical Association.